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Inhibitory Properties of the P1 Tyr Variant of Antithrombin

Antithrombin (AT) and protein Z-dependent protease inhibitor (ZPI) are among two physiological serpin inhibitors in plasma that are involved in the regulation of the clotting cascade. Unlike AT, which can inhibit the proteolytic activity of all coagulation proteases, ZPI has narrower protease specif...

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Bibliografiske detaljer
Main Authors: Yang, Likui, Manithody, Chandrashekhara, Qureshi, Shabir H., Rezaie, Alireza R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844450/
https://ncbi.nlm.nih.gov/pubmed/20184328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100120a
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