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Parkin Reverses Intracellular β-Amyloid Accumulation and Its Negative Effects on Proteasome Function
The significance of intracellular β-amyloid (Aβ(42)) accumulation is increasingly recognized in Alzheimer's disease (AD) pathogenesis. Aβ removal mechanisms that have attracted attention include IDE/neprilysin degradation and antibody-mediated uptake by immune cells. However, the role of the ub...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844439/ https://ncbi.nlm.nih.gov/pubmed/19610108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22178 |
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