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Degradation of Postsynaptic Scaffold GKAP and Regulation of Dendritic Spine Morphology by the TRIM3 Ubiquitin Ligase in Rat Hippocampal Neurons

Changes in neuronal activity modify the structure of dendritic spines and alter the function and protein composition of synapses. Regulated degradation of postsynaptic density (PSD) proteins by the ubiquitin-proteasome system is believed to play an important role in activity-dependent synaptic remod...

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Autori principali: Hung, Albert Y., Sung, Clifford C., Brito, Ilana L., Sheng, Morgan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844417/
https://ncbi.nlm.nih.gov/pubmed/20352094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009842
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