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The inflammasomes: mechanisms of activation and function
In response to injurious or infectious agents caspase-1 activating multiprotein complexes, termed inflammasomes, assemble in the cytoplasm of cells. Activated caspase-1 cleaves the pro-forms of the interleukin-1 cytokine family members leading to their activation and secretion. The IL-1 family cytok...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844336/ https://ncbi.nlm.nih.gov/pubmed/20060699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.12.004 |
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