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Activation and regulation of the inflammasomes

Inflammasomes are key signalling platforms that detect pathogenic microorganisms and sterile stressors, and that activate the highly pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18. In this Review, we discuss the complex regulatory mechanisms that facilitate a balanced but effective infl...

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Bibliografiska uppgifter
Huvudupphovsmän: Latz, Eicke, Xiao, T. Sam, Stutz, Andrea
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807999/
https://ncbi.nlm.nih.gov/pubmed/23702978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3452
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