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Ciz1 cooperates with cyclin-A–CDK2 to activate mammalian DNA replication in vitro
Initiation of mammalian DNA replication can be reconstituted from isolated G1-phase nuclei and cell extracts, supplemented with cyclin-dependent protein kinases (CDKs). Under these conditions, cyclin E supports pre-replication complex assembly, whereas cyclin-A-associated kinase acts later to termin...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844319/ https://ncbi.nlm.nih.gov/pubmed/20215406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.059345 |
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