Inhibition of Calcineurin-mediated Endocytosis and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Prevents Amyloid β Oligomer-induced Synaptic Disruption

Synaptic degeneration, including impairment of synaptic plasticity and loss of synapses, is an important feature of Alzheimer disease pathogenesis. Increasing evidence suggests that these degenerative synaptic changes are associated with an accumulation of soluble oligomeric assemblies of amyloid β...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Zhao, Wei-Qin, Santini, Francesca, Breese, Robert, Ross, Dave, Zhang, Xiaohua Douglas, Stone, David J., Ferrer, Marc, Townsend, Matthew, Wolfe, Abigail L., Seager, Matthew A., Kinney, Gene G., Shughrue, Paul J., Ray, William J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2010
Onderwerpen:
Neurobiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844209/
https://ncbi.nlm.nih.gov/pubmed/20032460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057182
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items