Src-induced Tyrosine Phosphorylation of VE-cadherin Is Not Sufficient to Decrease Barrier Function of Endothelial Monolayers

Activation of Src family kinases (SFK) and the subsequent phosphorylation of VE-cadherin have been proposed as major regulatory steps leading to increases in vascular permeability in response to inflammatory mediators and growth factors. To investigate Src signaling in the absence of parallel signal...

Full description

Saved in:
Bibliographic Details
Main Authors: Adam, Alejandro P., Sharenko, Amy L., Pumiglia, Kevin, Vincent, Peter A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844154/
https://ncbi.nlm.nih.gov/pubmed/20048167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079277
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items