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Regulation of endothelial barrier function by p120-catenin∙VE-cadherin interaction

Endothelial p120-catenin (p120) maintains the level of vascular endothelial cadherin (VE-Cad) by inhibiting VE-Cad endocytosis. Loss of p120 results in a decrease in VE-Cad levels, leading to the formation of monolayers with decreased barrier function (as assessed by transendothelial electrical resi...

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Publicat a:Mol Biol Cell
Autors principals: Garrett, Joshua P., Lowery, Anthony M., Adam, Alejandro P., Kowalczyk, Andrew P., Vincent, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221632/
https://ncbi.nlm.nih.gov/pubmed/27852896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-08-0616
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