p120-catenin binding masks an endocytic signal conserved in classical cadherins

p120-catenin (p120) binds to the cytoplasmic tails of classical cadherins and inhibits cadherin endocytosis. Although p120 regulation of cadherin internalization is thought to be important for adhesive junction dynamics, the mechanism by which p120 modulates cadherin endocytosis is unknown. In this...

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Main Authors: Nanes, Benjamin A., Chiasson-MacKenzie, Christine, Lowery, Anthony M., Ishiyama, Noboru, Faundez, Victor, Ikura, Mitsuhiko, Vincent, Peter A., Kowalczyk, Andrew P.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471230/
https://ncbi.nlm.nih.gov/pubmed/23071156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205029
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