p120-catenin regulates VE-cadherin endocytosis and degradation induced by the Kaposi sarcoma–associated ubiquitin ligase K5

Vascular endothelial (VE)-cadherin undergoes constitutive internalization driven by a unique endocytic motif that also serves as a p120-catenin (p120) binding site. p120 binding masks the motif, stabilizing the cadherin at cell junctions. This mechanism allows constitutive VE-cadherin endocytosis an...

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Publicat a:Mol Biol Cell
Autors principals: Nanes, Benjamin A., Grimsley-Myers, Cynthia M., Cadwell, Chantel M., Robinson, Brian S., Lowery, Anthony M., Vincent, Peter A., Mosunjac, Marina, Früh, Klaus, Kowalczyk, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2017
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221628/
https://ncbi.nlm.nih.gov/pubmed/27798235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0459
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