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Src-induced Tyrosine Phosphorylation of VE-cadherin Is Not Sufficient to Decrease Barrier Function of Endothelial Monolayers

Activation of Src family kinases (SFK) and the subsequent phosphorylation of VE-cadherin have been proposed as major regulatory steps leading to increases in vascular permeability in response to inflammatory mediators and growth factors. To investigate Src signaling in the absence of parallel signal...

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Detalhes bibliográficos
Main Authors: Adam, Alejandro P., Sharenko, Amy L., Pumiglia, Kevin, Vincent, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844154/
https://ncbi.nlm.nih.gov/pubmed/20048167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079277
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