Mycobacterium tuberculosis cAMP Receptor Protein (Rv3676) Differs from the Escherichia coli Paradigm in Its cAMP Binding and DNA Binding Properties and Transcription Activation Properties

The pathogen Mycobacterium tuberculosis produces a burst of cAMP upon infection of macrophages. Bacterial cyclic AMP receptor proteins (CRP) are transcription factors that respond to cAMP by binding at target promoters when cAMP concentrations increase. Rv3676 (CRP(Mt)) is a CRP family protein that...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stapleton, Melanie, Haq, Ihtshamul, Hunt, Debbie M., Arnvig, Kristine B., Artymiuk, Peter J., Buxton, Roger S., Green, Jeffrey
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Gene Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844151/
https://ncbi.nlm.nih.gov/pubmed/20028978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047720
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