Distinct Region-Specific α-Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration

Aggregation of α-synuclein (α-syn), a process that generates oligomeric intermediates, is a common pathological feature of several neurodegenerative disorders. Despite the potential importance of the oligomeric α-syn intermediates in neuron function, their biochemical properties and pathobiological...

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Autors principals: Tsika, Elpida, Moysidou, Maria, Guo, Jing, Cushman, Mimi, Gannon, Patrick, Sandaltzopoulos, Raphael, Giasson, Benoit I., Krainc, Dimitri, Ischiropoulos, Harry, Mazzulli, Joseph R.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844128/
https://ncbi.nlm.nih.gov/pubmed/20203200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4977-09.2010
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