A New α(5)β(1) Integrin-Dependent Survival Pathway Through GSK3β Activation in Leukemic Cells

BACKGROUND: Cell survival mediated by integrin engagement has been implicated in cell adhesion-mediated drug resistance. We have recently demonstrated that the activation of glycogen synthase kinase 3 β (GSK3β) is a new pathway supporting the chemoresistance of leukemic cells adhered to fibronectin....

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Bibliografiska uppgifter
Huvudupphovsmän: De Toni-Costes, Fabienne, Despeaux, Mathieu, Bertrand, Jessica, Bourogaa, Ezzeddine, Ysebaert, Loïc, Payrastre, Bernard, Racaud-Sultan, Claire
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843713/
https://ncbi.nlm.nih.gov/pubmed/20352103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009807
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