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A New α(5)β(1) Integrin-Dependent Survival Pathway Through GSK3β Activation in Leukemic Cells
BACKGROUND: Cell survival mediated by integrin engagement has been implicated in cell adhesion-mediated drug resistance. We have recently demonstrated that the activation of glycogen synthase kinase 3 β (GSK3β) is a new pathway supporting the chemoresistance of leukemic cells adhered to fibronectin....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843713/ https://ncbi.nlm.nih.gov/pubmed/20352103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009807 |
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