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Higher Matrix Stiffness Upregulates Osteopontin Expression in Hepatocellular Carcinoma Cells Mediated by Integrin β1/GSK3β/β-Catenin Signaling Pathway

Increased stromal stiffness is associated with hepatocellular carcinoma (HCC) development and progression. However, the molecular mechanism by which matrix stiffness stimuli modulate HCC progress is largely unknown. In this study, we explored whether matrix stiffness-mediated effects on osteopontin...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: You, Yang, Zheng, Qiongdan, Dong, Yinying, Wang, Yaohui, Zhang, Lan, Xue, Tongchun, Xie, Xiaoying, Hu, Chao, Wang, Zhiming, Chen, Rongxin, Wang, Yanhong, Cui, Jiefeng, Ren, Zhenggang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539226/
https://ncbi.nlm.nih.gov/pubmed/26280346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134243
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