PAR(2)-dependent activation of GSK3β regulates the survival of colon stem/progenitor cells

Protease-activated receptors PAR(1) and PAR(2) play an important role in the control of epithelial cell proliferation and migration. However, the survival of normal and tumor intestinal stem/progenitor cells promoted by proinflammatory mediators may be critical in oncogenesis. The glycogen synthase...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Nasri, Imen, Bonnet, Delphine, Zwarycz, Bailey, d'Aldebert, Emilie, Khou, Sokchea, Mezghani-Jarraya, Raoudha, Quaranta, Muriel, Rolland, Corinne, Bonnart, Chrystelle, Mas, Emmanuel, Ferrand, Audrey, Cenac, Nicolas, Magness, Scott, Van Landeghem, Laurianne, Vergnolle, Nathalie, Racaud-Sultan, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Stem Cells, Tissue Engineering, Development, and Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007290/
https://ncbi.nlm.nih.gov/pubmed/27313176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00328.2015
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