The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival

The type I insulin-like growth factor receptor (IGF1R) regulates multiple aspects of malignancy and is the target of several drugs currently in clinical trials. While IGF1R’s role in proliferation and survival is well-studied, the regulation of metastasis by IGF1R is not as clearly delineated. Previ...

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Hlavní autoři: Sachdev, Deepali, Zhang, Xihong, Matise, Ilze, Gaillard-Kelly, Martine, Yee, Douglas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843625/
https://ncbi.nlm.nih.gov/pubmed/19838209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.316
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