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Targeting insulin and insulin-like growth factor signaling in breast cancer

The insulin and insulin like growth factor (IGF) signaling systems are implicated in breast cancer biology. Thus, disrupting IGF/insulin signaling has been shown to have promise in a number of preclinical models. However, human clinical trials have been less promising. Despite evidence of some activ...

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Bibliographic Details
Main Authors: Yang, Yuzhe, Yee, Douglas
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534944/
https://ncbi.nlm.nih.gov/pubmed/23054135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-012-9268-y
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