Binding Site Turnover Produces Pervasive Quantitative Changes in Transcription Factor Binding between Closely Related Drosophila Species

Changes in gene expression play an important role in evolution, yet the molecular mechanisms underlying regulatory evolution are poorly understood. Here we compare genome-wide binding of the six transcription factors that initiate segmentation along the anterior-posterior axis in embryos of two clos...

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Detalhes bibliográficos
Main Authors: Bradley, Robert K., Li, Xiao-Yong, Trapnell, Cole, Davidson, Stuart, Pachter, Lior, Chu, Hou Cheng, Tonkin, Leath A., Biggin, Mark D., Eisen, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843597/
https://ncbi.nlm.nih.gov/pubmed/20351773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000343
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