The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding

BACKGROUND: In Drosophila embryos, many biochemically and functionally unrelated transcription factors bind quantitatively to highly overlapping sets of genomic regions, with much of the lowest levels of binding being incidental, non-functional interactions on DNA. The primary biochemical mechanisms...

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Hoofdauteurs: Li, Xiao-Yong, Thomas, Sean, Sabo, Peter J, Eisen, Michael B, Stamatoyannopoulos, John A, Biggin, Mark D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218860/
https://ncbi.nlm.nih.gov/pubmed/21473766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-4-r34
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