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Large-Scale Turnover of Functional Transcription Factor Binding Sites in Drosophila
The gain and loss of functional transcription factor binding sites has been proposed as a major source of evolutionary change in cis-regulatory DNA and gene expression. We have developed an evolutionary model to study binding-site turnover that uses multiple sequence alignments to assess the evoluti...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1599766/ https://ncbi.nlm.nih.gov/pubmed/17040121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020130 |
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