Transcription Factor Stat3 Stimulates Metastatic Behavior of Human Prostate Cancer Cells in Vivo, whereas Stat5b Has a Preferential Role in the Promotion of Prostate Cancer Cell Viability and Tumor Growth

Identification of the molecular changes that promote viability and metastatic behavior of prostate cancer is critical for the development of improved therapeutic interventions. Stat5a/b and Stat3 are both constitutively active in locally-confined and advanced prostate cancer, and both transcription...

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Detalhes bibliográficos
Main Authors: Gu, Lei, Dagvadorj, Ayush, Lutz, Jacqueline, Leiby, Benjamin, Bonuccelli, Gloria, Lisanti, Michael P., Addya, Sankar, Fortina, Paolo, Dasgupta, Abhijit, Hyslop, Terry, Bubendorf, Lukas, Nevalainen, Marja T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843484/
https://ncbi.nlm.nih.gov/pubmed/20167868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090653
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