N-Terminal Truncation of Stat5a/b Circumvents PIAS3-Mediated Transcriptional Inhibition of Stat5 in Prostate Cancer Cells

Transcription factor Stat5a/b is critical for prostate cancer cell survival and for prostate xenograft tumor growth. In addition, the Stat5a/b signaling pathway may contribute to progression of organ-confined prostate cancer to castration-resistant and/or metastatic disease. Expression of nuclear St...

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Main Authors: Dagvadorj, Ayush, Tan, Shyh-Han, Liao, Zhiyong, Xie, Jianwu, Nurmi, Martti, Alanen, Kalle, Rui, Hallgeir, Mirtti, Tuomas, Nevalainen, Marja T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982800/
https://ncbi.nlm.nih.gov/pubmed/20854925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2010.09.008
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