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STAT5A/B Gene Locus Undergoes Amplification during Human Prostate Cancer Progression

The molecular mechanisms underlying progression of prostate cancer (PCa) to castrate-resistant (CR) and metastatic disease are poorly understood. Our previous mechanistic work shows that inhibition of transcription factor Stat5 by multiple alternative methods induces extensive rapid apoptotic death...

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Autors principals: Haddad, Bassem R., Gu, Lei, Mirtti, Tuomas, Dagvadorj, Ayush, Vogiatzi, Paraskevi, Hoang, David T., Bajaj, Renu, Leiby, Benjamin, Ellsworth, Elyse, Blackmon, Shauna, Ruiz, Christian, Curtis, Mark, Fortina, Paolo, Ertel, Adam, Liu, Chengbao, Rui, Hallgeir, Visakorpi, Tapio, Bubendorf, Lukas, Lallas, Costas D., Trabulsi, Edouard J., McCue, Peter, Gomella, Leonard, Nevalainen, Marja T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668029/
https://ncbi.nlm.nih.gov/pubmed/23660011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.02.044
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