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In Vitro and in Vivo Enhanced Generation of Human A9 Dopamine Neurons from Neural Stem Cells by Bcl-X(L)

Human neural stem cells derived from the ventral mesencephalon (VM) are powerful research tools and candidates for cell therapies in Parkinson disease. Previous studies with VM dopaminergic neuron (DAn) precursors indicated poor growth potential and unstable phenotypical properties. Using the model...

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Détails bibliographiques
Auteurs principaux: Courtois, Elise T., Castillo, Claudia G., Seiz, Emma G., Ramos, Milagros, Bueno, Carlos, Liste, Isabel, Martínez-Serrano, Alberto
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843236/
https://ncbi.nlm.nih.gov/pubmed/20106970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.054312
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