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bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death.

Previous studies have implicated the bcl-2 protooncogene as a potential regulator of neuronal survival. However, mice lacking functional bcl-2 exhibited normal development and maintenance of the central nervous system (CNS). Since bcl-2 appears dispensable for neuronal survival, we have examined the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: González-García, M, García, I, Ding, L, O'Shea, S, Boise, L H, Thompson, C B, Núñez, G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41932/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753802/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4304
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