In Vitro and in Vivo Enhanced Generation of Human A9 Dopamine Neurons from Neural Stem Cells by Bcl-X(L)

Human neural stem cells derived from the ventral mesencephalon (VM) are powerful research tools and candidates for cell therapies in Parkinson disease. Previous studies with VM dopaminergic neuron (DAn) precursors indicated poor growth potential and unstable phenotypical properties. Using the model...

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Detalhes bibliográficos
Main Authors: Courtois, Elise T., Castillo, Claudia G., Seiz, Emma G., Ramos, Milagros, Bueno, Carlos, Liste, Isabel, Martínez-Serrano, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843236/
https://ncbi.nlm.nih.gov/pubmed/20106970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.054312
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