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Low Density Subcellular Fractions Enhance Disease-specific Prion Protein Misfolding

The production of prion particles in vitro by amplification with or without exogenous seed typically results in infectivity titers less than those associated with PrP(Sc) isolated ex vivo and highlights the potential role of co-factors that can catalyze disease-specific prion protein misfolding in v...

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Detalhes bibliográficos
Main Authors: Graham, James F., Agarwal, Sonya, Kurian, Dominic, Kirby, Louise, Pinheiro, Teresa J. T., Gill, Andrew C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843235/
https://ncbi.nlm.nih.gov/pubmed/20106973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093484
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