Altered Function of the SCN1A Voltage-gated Sodium Channel Leads to γ-Aminobutyric Acid-ergic (GABAergic) Interneuron Abnormalities

Voltage-gated sodium channels are required for the initiation and propagation of action potentials. Mutations in the neuronal voltage-gated sodium channel SCN1A are associated with a growing number of disorders including generalized epilepsy with febrile seizures plus (GEFS+),(7) severe myoclonic ep...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Martin, Melinda S., Dutt, Karoni, Papale, Ligia A., Dubé, Céline M., Dutton, Stacey B., de Haan, Georgius, Shankar, Anupama, Tufik, Sergio, Meisler, Miriam H., Baram, Tallie Z., Goldin, Alan L., Escayg, Andrew
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Neurobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843231/
https://ncbi.nlm.nih.gov/pubmed/20100831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078568
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares