An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior

Understanding the role of SCN8A in epilepsy and behavior is critical in light of recently identified human SCN8A epilepsy mutations. We have previously demonstrated that Scn8a(med) and Scn8a(med-jo) mice carrying mutations in the Scn8a gene display increased resistance to flurothyl and kainic acid-i...

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Bibliografiska uppgifter
I publikationen:Exp Neurol
Huvudupphovsmän: Makinson, Christopher D., Dutt, Karoni, Lin, Frank, Papale, Ligia A., Shankar, Anupama, Barela, Arthur J., Liu, Robert, Goldin, Alan L., Escayg, Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688066/
https://ncbi.nlm.nih.gov/pubmed/26410685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.09.008
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