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Role of the hippocampus in Na(v)1.6 (Scn8a) mediated seizure resistance
SCN1A mutations are the main cause of the epilepsy disorders Dravet syndrome (DS) and genetic epilepsy with febrile seizures plus (GEFS+). Mutations that reduce the activity of the mouse Scn8a gene, in contrast, are found to confer seizure resistance and extend the lifespan of mouse models of DS and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077284/ https://ncbi.nlm.nih.gov/pubmed/24704313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.03.014 |
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