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Structure of the Antibiotic Resistance Factor Spectinomycin Phosphotransferase from Legionella pneumophila

Aminoglycoside phosphotransferases (APHs) constitute a diverse group of enzymes that are often the underlying cause of aminoglycoside resistance in the clinical setting. Several APHs have been extensively characterized, including the elucidation of the three-dimensional structure of two APH(3′) isoz...

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Detalhes bibliográficos
Main Authors: Fong, Desiree H., Lemke, Christopher T., Hwang, Jiyoung, Xiong, Bing, Berghuis, Albert M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843205/
https://ncbi.nlm.nih.gov/pubmed/20089863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038364
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