Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase

γ-Aminobutyric acid (GABA), the major inhibitory neurotransmitter in the mammalian brain, is synthesized by two glutamate decarboxylase isoforms, GAD65 and GAD67. The separate role of the two isoforms is unknown, but differences in saturation with cofactor and subcellular localization suggest that G...

Full description

Saved in:
Bibliographic Details
Main Authors: Kash, Shera F., Johnson, Randall S., Tecott, Laurence H., Noebels, Jeffrey L., Mayfield, R. Dayne, Hanahan, Douglas, Baekkeskov, Steinunn
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC28432/
https://ncbi.nlm.nih.gov/pubmed/9391152
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items