Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase
γ-Aminobutyric acid (GABA), the major inhibitory neurotransmitter in the mammalian brain, is synthesized by two glutamate decarboxylase isoforms, GAD65 and GAD67. The separate role of the two isoforms is unknown, but differences in saturation with cofactor and subcellular localization suggest that G...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9391152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.25.14060 |
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