The Angelman Syndrome-associated ubiquitin ligase Ube3A regulates synapse development by ubiquitinating Arc

Angelman Syndrome is a debilitating neurological disorder caused by mutation of the E3 ubiquitin ligase Ube3A, a gene whose mutation has also recently been associated with autism spectrum disorders (ASDs). The function of Ube3A during nervous system development, and how Ube3A mutations give rise to...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Greer, Paul L., Hanayama, Rikinari, Bloodgood, Brenda L., Mardinly, Alan R., Lipton, David M., Flavell, Steven W., Kim, Tae-Kyung, Griffith, Eric C., Waldon, Zachary, Maehr, Rene, Ploegh, Hidde L., Chowdhury, Shoaib, Worley, Paul F., Steen, Judith, Greenberg, Michael E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2010
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843143/
https://ncbi.nlm.nih.gov/pubmed/20211139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.01.026
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