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High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L)
Justification for article appearing in Angewandte Chemie: Foldamers are currently being explored by a number of groups as antagonists of protein-protein interactions. Here we report the first high-resolution structure of a foldamer in complex with its target protein, the anti-apoptotic protein Bcl-x...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843084/ https://ncbi.nlm.nih.gov/pubmed/19229915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200805761 |
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