High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L)

Justification for article appearing in Angewandte Chemie: Foldamers are currently being explored by a number of groups as antagonists of protein-protein interactions. Here we report the first high-resolution structure of a foldamer in complex with its target protein, the anti-apoptotic protein Bcl-x...

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Detalhes bibliográficos
Main Authors: Lee, Erinna F., Sadowsky, Jack D., Smith, Brian J., Czabotar, Peter E., Peterson-Kaufman, Kimberly J., Colman, Peter M., Gellman, Samuel H., Fairlie, W. Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843084/
https://ncbi.nlm.nih.gov/pubmed/19229915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200805761
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