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Mevalonate Analogues as Substrates of Enzymes in the Isoprenoid Biosynthetic Pathway of Streptococcus pneumoniae

Survival of the human pathogen Streptococcus pneumoniae requires a functional mevalonate pathway, which produces isopentenyl diphosphate, the essential building block of isoprenoids. Flux through this pathway appears to be regulated at the mevalonate kinase (MK) step, which is strongly feedback-inhi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Kudoh, Takashi, Park, Chan Sun, Lefurgy, Scott T., Sun, Meihao, Michels, Theodore, Leyh, Thomas S., Silverman, Richard B.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842986/
https://ncbi.nlm.nih.gov/pubmed/20056424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.12.050
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