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Crystal structure of the Streptococcus pneumoniae mevalonate kinase in complex with diphosphomevalonate

Streptococcus pneumoniae, a ubiquitous gram-positive pathogen with an alarming, steadily evolving resistance to frontline antimicrobials, poses a severe global health threat both in the community and in the clinic. The recent discovery that diphosphomevalonate (DPM), an essential intermediate in the...

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Détails bibliographiques
Auteurs principaux: Andreassi, John L., Bilder, Patrick W., Vetting, Matthew W., Roderick, Steven L., Leyh, Thomas S.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206640/
https://ncbi.nlm.nih.gov/pubmed/17400916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072755707
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