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Determination of primary structure and microheterogeneity of a β-amyloid plaque-specific antibody using high performance LC- tandem mass spectrometry
Using the “bottom-up” approach and liquid chromatography in combination with mass spectrometry, the primary structure and sequence microheterogeneity of a plaque-specific anti-β-amyloid (1–17) monoclonal antibody (clone 6E10) was characterized. This study describes the extent of structural informati...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842979/ https://ncbi.nlm.nih.gov/pubmed/18369607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-008-1941-z |
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