Elucidation of O-glycosylation structures of the ß-amyloid precursor protein by liquid chromatography - mass spectrometry using electron transfer dissociation and collision induced dissociation

Accumulation and deposition of ß-amyloid peptide, a major constituent in neuritic plaques are hallmarks of Alzheimer’s disease (AD) and AD-related neurodegenerative diseases. ß-Amyloid (Aß) is derived from the proteolytic cleavage of amyloid precursor protein (APP), a transmembrane protein present i...

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Main Authors: Perdivara, Irina, Petrovich, Robert, Alliquant, Bernadette, Deterding, Leesa J., Tomer, Kenneth B., Przybylski, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743936/
https://ncbi.nlm.nih.gov/pubmed/19093876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr800758g
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