Reconstitution of Heterochromatin-Dependent Transcriptional Gene Silencing

Heterochromatin assembly in budding yeast requires the SIR complex, which contains the NAD-dependent deacetylase Sir2 and the Sir3 and Sir4 proteins. Sir3 binds to nucleosomes containing deacetylated histone H4 lysine 16 (H4K16) and, with Sir4, promotes spreading of Sir2 and deacetylation along the...

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Bibliografski detalji
Glavni autori: Johnson, Aaron, Li, Geng, Sikorski, Timothy W., Buratowski, Stephen, Woodcock, Christopher L., Moazed, Danesh
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842978/
https://ncbi.nlm.nih.gov/pubmed/19782027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.030
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