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The Basal Initiation Machinery: Beyond the General Transcription Factors

In vitro experiments led to a simple model in which basal transcription factors sequentially assembled with RNA Polymerase II to generate a preinitiation complex (PIC). Emerging evidence indicates that PIC composition is not universal, but promoter-dependent. Active promoters are occupied by a mixed...

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Detalhes bibliográficos
Main Authors: Sikorski, Timothy W., Buratowski, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692371/
https://ncbi.nlm.nih.gov/pubmed/19411170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2009.03.006
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