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Heterochromatic Gene Silencing by Activator Interference and a Transcription Elongation Barrier

Heterochromatin silences transcription, contributing to development, differentiation, and genome stability in eukaryotic organisms. Budding yeast heterochromatic silencing is strictly dependent on the silent information regulator (SIR) complex composed of the Sir2 histone deacetylase and the chromat...

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Detalhes bibliográficos
Main Authors: Johnson, Aaron, Wu, Ronghu, Peetz, Matthew, Gygi, Steven P., Moazed, Danesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789973/
https://ncbi.nlm.nih.gov/pubmed/23940036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460071
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