Heterochromatic Gene Silencing by Activator Interference and a Transcription Elongation Barrier

Heterochromatin silences transcription, contributing to development, differentiation, and genome stability in eukaryotic organisms. Budding yeast heterochromatic silencing is strictly dependent on the silent information regulator (SIR) complex composed of the Sir2 histone deacetylase and the chromat...

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Bibliographic Details
Main Authors: Johnson, Aaron, Wu, Ronghu, Peetz, Matthew, Gygi, Steven P., Moazed, Danesh
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789973/
https://ncbi.nlm.nih.gov/pubmed/23940036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460071
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