Histone Deacetylase Inhibitors Improve In Vitro and In Vivo Developmental Competence of Somatic Cell Nuclear Transfer Porcine Embryos

Faulty epigenetic reprogramming of somatic nuclei is likely to be a major cause of low success observed in all mammals produced through somatic cell nuclear transfer (SCNT). It has been demonstrated that the developmental competence of SCNT embryos in several species were significantly enhanced via...

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Detalhes bibliográficos
Main Authors: Zhao, Jianguo, Hao, Yanhong, Ross, Jason W., Spate, Lee D., Walters, Eric M., Samuel, Melissa S., Rieke, August, Murphy, Clifton N., Prather, Randall S.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842950/
https://ncbi.nlm.nih.gov/pubmed/20132015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2009.0038
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