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Significant Improvement in Cloning Efficiency of an Inbred Miniature Pig by Histone Deacetylase Inhibitor Treatment after Somatic Cell Nuclear Transfer

The National Institutes of Health (NIH) miniature pig was developed specifically for xenotransplantation and has been extensively used as a large-animal model in many other biomedical experiments. However, the cloning efficiency of this pig is very low (<0.2%), and this has been an obstacle to th...

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Detalhes bibliográficos
Main Authors: Zhao, Jianguo, Ross, Jason W., Hao, Yanhong, Spate, Lee D., Walters, Eric M., Samuel, Melissa S., Rieke, August, Murphy, Clifton N., Prather, Randall S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731980/
https://ncbi.nlm.nih.gov/pubmed/19386991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.077016
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