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Generation of an Inbred Miniature Pig Model of Retinitis Pigmentosa

PURPOSE. The Pro23His (P23H) rhodopsin (RHO) mutation underlies the most common form of human autosomal dominant retinitis pigmentosa (adRP). The objective of this investigation was to establish a transgenic miniature swine model of RP using the human P23H RHO gene. METHODS. Somatic cell nuclear tra...

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Main Authors: Ross, Jason W., Fernandez de Castro, Juan P., Zhao, Jianguo, Samuel, Melissa, Walters, Eric, Rios, Cecilia, Bray-Ward, Patricia, Jones, Bryan W., Marc, Robert E., Wang, Wei, Zhou, Liang, Noel, Jennifer M., McCall, Maureen A., DeMarco, Paul J., Prather, Randall S., Kaplan, Henry J.
Format: Artigo
Jezik:Inglês
Izdano: Association for Research in Vision and Ophthalmology, Inc. 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292381/
https://ncbi.nlm.nih.gov/pubmed/22247487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8784
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