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Expression of t-DARPP Mediates Trastuzumab Resistance in Breast Cancer Cells

PURPOSE: We have investigated the role of t-DARPP in trastuzumab resistance in ERBB2-amplified and overexpressed breast cancer cell lines. EXPERIMENTAL DESIGN: We have used the HR-5 and HR-6 trastuzumab-resistant cells that were established from tumors that recurred in the presence of trastuzumab th...

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Bibliographische Detailangaben
Hauptverfasser: Belkhiri, Abbes, Dar, Altaf A., Peng, DunFa, Razvi, Mohammad H., Rinehart, Cammie, Arteaga, Carlos L., El-Rifai, Wael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842884/
https://ncbi.nlm.nih.gov/pubmed/18579663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0121
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