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A Role for Copper in the Toxicity of Zinc-Deficient Superoxide Dismutase to Motor Neurons in Amyotrophic Lateral Sclerosis

In the 16 years since mutations to copper, zinc superoxide dismutase (SOD1) were first linked to familial amyotrophic lateral sclerosis (ALS), a multitude of apparently contradictory results have prevented any general consensus to emerge about the mechanism of toxicity. A decade ago, we showed that...

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Bibliografiset tiedot
Päätekijät: Trumbull, Kari A., Beckman, Joseph S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842582/
https://ncbi.nlm.nih.gov/pubmed/19309264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2574
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